The mainstay endoscopic resection is EMR. The vast majority of literature and clinical practice is using EMR in the colon. EMR can be used elsewhere in the gut however the primary role is colonic polyp resection. EMR has been extensively studied especially in comparison to ESD. EMR achieves complete lesion resection equal to ESD with similar rates of surgery for failures. The main issues that need addressing are post polypectomy bleeding and polyp recurrence rates. New modalities are showing promise in reducing these rates including underwater EMR techniques, wider fields of resection or ablation and clip application. For difficult polyps such as non-lifting lesions and appendiceal polyps there is a role for the FTRD.