Dr. Clarke received his undergraduate degree from Brown University, where he graduated Phi Beta Kappa and magna cum laude with departmental honors. He received his medical degree from the College of Physicians & Surgeons at Columbia University, where he was elected to AOA. He moved to Baltimore, Maryland to pursue internship and residency in Internal Medicine at Johns Hopkins University, followed by a fellowship in Gastroenterology and Hepatology also at Johns Hopkins University and advanced motility training at Northwestern University under the direction of Drs. Peter Kahrilas and John Pandolfino, before returning to Johns Hopkins University as faculty in 2007. While at Johns Hopkins University, he was an Associate Professor in the Department of Medicine, the Clinical Director of the Johns Hopkins Center for Neurogastroenterology and GI Motility, and the Clinical Director of the Division of Gastroenterology and Hepatology at Johns Hopkins Bayview Medical Center. He moved to Stanford University in 2016 as Director of the Esophageal Program and is now a Clinical Professor of Medicine. His clinical and research interests include dysphagia, eosinophilic esophagitis, gastroesophageal reflux, achalasia, esophageal motility disorders, GI manifestations of systemic disorders such as scleroderma and amyloidosis, and gastroparesis.