Yoshio Yamaoka, M.D., Ph.D. is the Dean, Oita University Faculty of Medicine, Japan, and is the Chair and Professor of the Department of Environmental and Preventive Medicine at the University. He is also a Professor in the Department of Gastroenterology at the Baylor College of Medicine, USA. Professor Yamaoka received M.D., and Ph.D. in gastroenterology from Kyoto Prefectural University of Medicine, Japan and post graduate training in Internal Medicine and Gastroenterology from the same university. Then, he did post-doctoral work in the Department of Medicine, Section of Gastroenterology at Baylor College of Medicine before joining the faculty of the same section in 2001. Currently, he is also a visiting Professor at Mongolian National University of Medical Sciences, Mongolia, an adjunct Professor at Airlangga University, Indonesia, Visiting professor at University Malaysia Sabah, Malaysia, and a Bualuang ASEAN Chair Professor at Thammasat University, Thailand. He is an Associate Editor of the World Journal of Gastroenterology, Gut Pathogens, PLoS ONE, Scientific Reports, and Gastroenterology Research and Practice. He is the editor of 3 international books: “Helicobacter pylori: Molecular genetics and cellular biology”, “Helicobacter pylori Research from Bench to Bedside” and “Microbiota; Current Research and Emerging Trends”. He has more than 400 International publications with impact factor more than 1,800 (Scopus; h-index 64). He is working on the mechanisms regulating the development of gastric cancer in H. pylori infection, including the discovery of novel virulence factors; OipA and DupA. He also investigates the human migration patterns based on the H. pylori genomes, and found that H. pylori was present at least 58,000 years ago in Africa and spread into the world with changing the toxicity.