Dr. Haruhiro Inoue is a world-renowned surgeon and endoscopist. He is a professor at Showa University and Chairman of the Digestive Disease Center at Showa University Koto Toyosu Hospital in Tokyo. Dr. Inoue graduated from Yamaguchi University School of Medicine in 1983. In 2009, he was promoted to a full professor at Showa University, where he served as a chair of the Showa University International Training Center for Endoscopy and Surgical endoscopy (SUITES).　In 2014, he moved currently working hospital and serve as a professor and chair of Digestive Diseases Center. Dr. Inoue’s clinical achievements are wide-ranging. In 1992, he developed a technique (cap-EMR) that simplified the performance of endoscopic mucosal resection (EMR). In 2000, he reported the world’s first EMR for Barrett’s intramucosal cancer, and in 2003, he again reported a circumferential EMR for Barrett’s esophagus with high grade dysplasia. In 2008, he performed the world’s first case of POEM, and to date his team has treated more than 2100 achalasia patients. In 2014, he reported the endoscopic removal of a submucosal tumor using a POEM-like procedure, per-oral endoscopic tumor resection (POET). Also in 2014, he reported antireflux mucosectmy (ARMS) for PPI-resistant GERD. Now it advanced as antireflux mucosal ablation (ARMA). In 2019, he reported POEM+F (POEM+fundoplication) as a pure NOTES surgery for PPI refractory GERD. Dr. Inoue is an honorary member of the Russian Society of Endoscopy, and the German Society of Radiology and Digestive Endoscopy. In 2008, he has become a Fellow of ASGE, and he was honored twice with the society’s Crystal award (2006 and 2013). In 2011, he received the Pioneer in Endoscopy Award from the Society of American gastrointestinal and endoscopic Surgeons (SAGES). In 2017, he received the Bushell Lecture Award from Australian society of gastroenterology.